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Sigma-Aldrich

EVEROLIMUS (C005B-310920)

Application Everolimus has been used as an mechanistic target of rapamycin complex 1 (mTORC1) inhibitor to study its effect on MCF7 and MDA-MB-231 cell lines. Biochem/physiol Actions Everolimus, a substrate for P-glycoprotein (P-gp) can be used

Description

Application

Everolimus has been used as an mechanistic target of rapamycin complex 1 (mTORC1) inhibitor to study its effect on MCF7 and MDA-MB-231 cell lines.

Biochem/physiol Actions

Everolimus, a substrate for P-glycoprotein (P-gp) can be used to treat advanced neuroendocrine tumors (NETs).

Everolimus, the 40-O-(2-hydroxyethyl) derivative of rapamycin (sirolimus), is a potent and selective inhibitor of mechanistic target of rapamycin (mTOR). Everolimus is selective for the mTORC1 protein complex. Everolimus exhibit potent immunosuppressive and anticancer activities.

Specifications
UPC:
51112605
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
10
Unit of Measurement:
MG
MPN:
SML2282-10MG
CAS:
159351-69-6
Catalog No. C005B-310920
Price: $319.92
List Price: $355.46
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