F-1

F-1 is a potent dual inhibitor of ALK and ROS1 that suppresses phospho-ALK and its relative downstream signaling pathways with IC50 of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.

Specifications & Purity: F-1 is a potent dual inhibitor of ALK and ROS1 that suppresses phospho-ALK and its relative downstream signaling pathways with IC50 of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.

Molecular Formula: C22H27ClN8O3S

Molecular Weight: 519.02

PubChem CID: 138454747

Isomeric SMILES: CN1CCN(CC1)C2=NC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl)OC

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51442002

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

F412387-1mg

Country of Origin:

China

CAS:

2244775-31-1

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90