FENOLDOPAM MESYLATE SALT (C005B-313685)

Application

Fenoldopam mesylate may be used to study dopamine D₁-mediated cell signaling.

Biochem/physiol Actions

Fenoldopam mesylate (FM) is considered as an effective therapeutic agent to prevent the onset of postoperative AKI (PO-AKI). In healthy cats, FM can stimulate diuresis and be well-tolerated. This benzazepine-derivative is regional specific and does not cause cerebral vasodilation.

Fenoldopam mesylate is a selective dopamine D₁ receptor agonist used as an antihypertensive agent. It is an agonist for D₁-like dopamine receptors and binds with moderate affinity to α2-adrenoceptors. It has no significant affinity for D₂-like receptors, α1 and α-adrenoceptors, 5HT₁ and 5HT₂ receptors, or muscarinic receptors. Fenoldopam mesylate causes peripheral vasodilation by stimulating dopamine-1receptors and α2-adrenoceptors, increasing renal blood flow.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:

51151640

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

10

Unit of Measurement:

MG

MPN:

SML0198-10MG

CAS:

67227-57-0