Fluorinated VHL spy molecule 3 (C007B-168582)

DescriptionFluorinated VHL Spy Molecule 3 can be used for the discovery of new von Hippel-Lindau (VHL) binders. Based on VH032 (cat#901490), this reporter was designed in the lab ofAlessio Ciullito bind the hydroxyproline (Hyp) recognition site of VHL. When used in competition ligand-observed 19F NMR screening experiments, its displacement indicates binding by another molecule. Additional Fluorinated VHL Spy Molecules are available as listings909416,909432, and909459.The E3 ligase VHL is of growing interest fortargeted protein degradation, and these spy molecules will facilitate the identification of novel VHL ligands and VHL-based degraders. Specification: ≥95% Molecular Formula: C18H18F3N3O3S Molecular Weight: 413.41 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/F463447-SCI_bbae69a1b4b5106f05c5018e09f21f86.pdf

UPC:

41115701

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

F463447-100mg

CAS:

2290526-29-1

Product Size:

100mg