FMOC-PAL AM RESIN 5 G (C005B-234687)

General description

Fmoc-PAL-AM resin consists of Barany′s aminomethyl-dimethoxyphenoxyvaleric acid linker ^[1] attached to aminomethylated polystyrene. The amino group of this linker can be easily acylated under standard coupling conditions. Following peptide assembly, treatment with 95% TFA containing scavengers releases the desired peptide amide. Studies have shown the acid sensitivity of this linker to be around twice that of the Rink amide linker ^[2]. There is some evidence to suggest that PAL resins give greater yields in microwave assisted synthesis.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Analysis Note

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.50 - 0.80 mmol/g
Swelling Volume (in DMF): lot specific result

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Quality Level: 200. product line: Novabiochem^®. . form: beads. reaction suitability: reaction type: Fmoc solid-phase peptide synthesis. manufacturer/tradename: Novabiochem^®. . application(s): peptide synthesis. functional group: Fmoc, amine. storage temp.: 2-8°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

UPC:

51203100

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

5

Unit of Measurement:

GR

MPN:

8551330005