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Sigma-Aldrich

FRIEDELIN TECH.

Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis , Celastrus vulcanicola , Terminalia avicennioides , and Alangium salvifolium . It is known to act as a histamine H1 receptor (H1R) antagonist,

Description

General description

Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor (H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent.

Application

Friedelin can be used as a starting material in the synthesis of:

  • Friedel-3-enol acetate, friedel-2-oxo-3-enol acetate, friedel-2-ene derivatives and friedelin ketoxime.
  • Oxygenated friedelin derivatives as potent DNA topoisomerase IIα inhibitors.
  • Its 1,4-pyrazine derivatives as potent antimicrobial agents.

Specifications
UPC:
51373003
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
1
Unit of Measurement:
GR
MPN:
855022-1G
CAS:
559-74-0
Catalog No. C005B-048786
Price: $766.22
List Price: $851.35
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