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Sigma-Aldrich

FSL-1

Biochem/physiol Actions FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF- K B. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein

Description

Biochem/physiol Actions

FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein LP44 of Mycoplasma salivarium. FSL-1 showed higher stimulatory activity than MALP-2 in its ability to induce TNF-α production in macrophages and NF-κB in TLR2/TLR6 transfected HEK293 cells.

FSL-1 is a bacterial-derived toll-like receptor 2/6 agonist. It is capable of increasing resistance to herpes simplex virus type 2 (HSV-2) infection.

Reconstitution

Reconstitute in endotoxin-free water.

Other Notes

Air sensitive

Specifications
UPC:
51286202
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
1
Unit of Measurement:
EA
MPN:
SML1420-100UG
CAS:
322455-70-9
Catalog No. C005B-312128
Price: $628.69
List Price: $698.54
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