Fumitremorgin C (C007B-185874)

Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1). Specification: 0.95 MDL Number: MFCD08702652 Molecular Formula: C22H25N3O3 Molecular Weight: 379.45 PubChem CID: 403923 Isomeric SMILES: CC(=C[C@H]1C2=C(C[C@@H]3N1C(=O)[C@@H]4CCCN4C3=O)C5=C(N2)C=C(C=C5)OC)C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/F492230-SCI_eadbceaeb8904ef795a45a7bfb026400.pdf

UPC:

51111744

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

F492230-1mg

CAS:

118974-02-0

Product Size:

1mg