GO 6983 (C005B-015228)

Application

GO6983 has been used as a protein kinase C (PKC) inhibitor to study its effects on the nuclear import. It has also been used as a supplement in Fc medium to culture mouse embryonic stem (mES) cells on mitomycin C treated mouse embryonic fibroblasts (MEFs).

Biochem/physiol Actions

Protein kinase C (PKC) inhibitor that selectively inhibits several PKC isozymes (IC₅₀ = 7 nM for PKCα and PKCβ; 6 nM for PKCγ; 10 nM for PKCδ; and 60 nM for PKCζ), but does not inhibit PKCμ (IC₅₀ = 20 mM).

UPC:

51111850

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

500

Unit of Measurement:

UG

MPN:

G1918-500UG

CAS:

133053-19-7