Gallopamil hydrochloride (C007B-357344)

Gallopamil hydrochloride (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC 50 of 10.9 μM . Gallopamil hydrochloride is a potent antiarrhythmic and vasodilator agent .In VivoGallopamil hydrochloride (Methoxyverapamil hydrochloride; i.v.; 0.2 mg/kg; for 5 min) markedly reduces ventricular tachycardia (VT) and totally prevents fibrillation (VF). Gallopamil significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wistar rats weighing 290-370 gDosage: 0.2 mg/kg Administration: i.v.; 5 min Result: Markedly reduced VT and totally prevented VF.Form:Solid. Specification: ≥98.0% Molecular Formula: C28H41ClN2O5 Molecular Weight: 521.1 PubChem CID: 119442 Isomeric SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C(=C2)OC)OC)OC.Cl

UPC:

51431611

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

WeightUOM:

LB

MPN:

G647826-1mg

CAS:

16662-46-7

Product Size:

1mg