Sigma-Aldrich
GLOBOMYCIN FROM STREPTOMYCES HAGRONENSIS
Globomycin is a cyclic peptide antibiotic, which inhibits the growth of enteric Gram-negative bacteria through cell wall synthesis inhibition. Biochem/physiol Actions Globomycin was found to inhibit LspA, a lipoprotein signal peptidase.
Description
General description
Globomycin is a cyclic peptide antibiotic, which inhibits the growth of enteric Gram-negative bacteria through cell wall synthesis inhibition.
Biochem/physiol Actions
Globomycin was found to inhibit LspA, a lipoprotein signal peptidase. It eliminates the maturation of pro-lipoproteins by inhibition of the enzyme that converts pro-lipoprotein to lipoprotein, acting as a substrate analog of the signal sequence in the outer membrane of Gram-negative bacteria.
Specifications
- UPC:
- 51281674
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- MG
- MPN:
- G1424-1MG
- CAS:
- 67076-74-8
Catalog No.
C005B-056132
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