Glucocorticoid receptor agonist-2

Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC 50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373.In VitroGlucocorticoid receptor agonist-2 shows glucocorticoid receptor (GR) and progersterone receptor (PR) binding activities with IC 50 values of 6.6 and 7.3 nM, respectively. Glucocorticoid receptor agonist-2 shows EC 50 values of 0.2 and 442 nM to glucocorticoid responsive element (GRE) reporter and mineralcorticoid receptor (MR), respectively. Glucocorticoid receptor agonist-2 agonists MR with an EC 50 value of 149 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid. Specification: 0.99 Molecular Formula: C34H35F2NO7 Molecular Weight: 607.64

UPC:

51422512

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

G650411-5mg

CAS:

2166378-92-1

Product Size:

5mg