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MILLIPORE SIGMA

Glycine

Glycine is the simplest amino acid building block. Application Glycine has been used in whole-cell patch clamp recording to measure inward NMDA ( N -methyl- D -aspartate) currents.

Description

General description

Glycine is the simplest amino acid building block.

Application

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Specifications
UPC:
51151611
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
50
Unit of Measurement:
G
WeightUOM:
LB
MPN:
410225
CAS Number:
56-40-6
Catalog No. C005B-542342
Price: $117.40
List Price: $130.44
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