GSK2807 Trifluoroacetate (C007B-357735)

GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3 , with a K i of 14 nM and an IC 50 of 130 nMIn VitroA high-resolution crystal structure reveals that GSK2807 bridges the gap between the SAM-binding pocket and the substrate lysine tunnel of SMYD3. GSK2807 is 24-fold selective for SMYD3 in comparison with the closely related enzyme SMYD2 (K i =14±6 nM and 345±36 nM, respectively). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:SMYD3|14 nM (Ki)|SMYD3|130 nM (IC|50|). Specification: 0.99 Molecular Formula: C21H33F3N8O7 Molecular Weight: 566.5 PubChem CID: 134814505

UPC:

51373425

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

G649932-50mg

CAS:

2245255-66-5

Product Size:

50mg