GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3 , with a K i of 14 nM and an IC 50 of 130 nMIn VitroA high-resolution crystal structure reveals that GSK2807 bridges the gap between the SAM-binding pocket and the substrate lysine tunnel of SMYD3. GSK2807 is 24-fold selective for SMYD3 in comparison with the closely related enzyme SMYD2 (K i =14±6 nM and 345±36 nM, respectively). MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:SMYD3|14 nM (Ki)|SMYD3|130 nM (IC|50|). Specification: 10mM in DMSO Molecular Formula: C21H33F3N8O7 Molecular Weight: 566.5
- UPC:
- 12352101
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- G656060-1ml
- CAS:
- 2245255-66-5
- Product Size:
- 1ml
