H-L-PHOTO-PROLINE HCL (C005B-236178)

Application

H-L-Photo-Proline HCl is a diazirine-containing proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907324.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

Molecular Weight: 177.59. Empirical Formula: C₅H₈ClN₃O₂. Assay: ≥. 95%. form: powder. reaction suitability: reaction type: solution phase peptide synthesis. application(s): peptide synthesis. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

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UPC:

51131737

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

100

Unit of Measurement:

MG

MPN:

907286-100MG

Temperature Control Device:

Yes

Controlled Substances and Cyanide:

Yes