Hydroxylamine hydrochloride

General description

Hydroxylamine hydrochloride (NH₂OH.HCl) is a hygroscopic salt widely used as a reactant in electrophilic substitution reactions, oxidation, and reduction reactions. It is also used in the synthesis of nitriles, pyrazoles, isoxazoles, nitrones, and pyridine.

Hydroxylamine hydrochloride (Hydroxylammonium chloride) participates in the synthesis of 1,2,4-oxadiazoles, secondary amides and tertiary amides.

Application

Hydroxylamine hydrochloride can be used as a reactant:

• in the synthesis of primary amides from aldehydes in the presence of cesium carbonate (Cs₂CO₃) as a catalyst.
• in the conversion of alicyclic /aliphatic carbonyl compounds and the aromatic aldehydes into corresponding oximes.
• in the one-pot synthesis of nitriles from aldehydes in the presence of sodium sulfate (anhyd) and sodium bicarbonate catalysts.
• It can also be used as a reducing agent in the preparation of single-layer reduced graphene oxide (RGO) sheets and films.

Biochem/physiol Actions

MAO inhibitor; inhibits platelet aggregation.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

UPC:

51142044

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

100

Unit of Measurement:

G

WeightUOM:

LB

MPN:

159417

CAS Number:

1304222