Sigma-Aldrich
ICILIN (C005B-036280)
Icilin is a synthetic cooling agent and modulates human transient receptor potential cation channel (TRPA1). Icilin inhibits transient receptor potential cation channel subfamily M member 8 (TRPM8) and modulates calcium release.
Description
General description
Icilin is a synthetic cooling agent and modulates human transient receptor potential cation channel (TRPA1). Icilin inhibits transient receptor potential cation channel subfamily M member 8 (TRPM8) and modulates calcium release. Icilin also suppresses transient receptor potential vanilloid subtype 3 (TRPV3).
Application
Icilin has been used as cooling agent in anterior ventromedial preoptic area (VMPO) neurons.
Biochem/physiol Actions
Icilin is a potent agonist at the CMR1 cold- and menthol-sensitive receptor.
Specifications
- UPC:
- 51152013
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 10
- Unit of Measurement:
- MG
- MPN:
- I9532-10MG
- CAS:
- 36945-98-9
Catalog No.
C005B-036280
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