IDH-305

IDH-305 IDH-305 (Compound 13) is an orally available, mutant-selective and brain-penetrant inhibitor of isocitrate dehydrogenase 1 (IDH1) that targets IDH1(R132) mutation with IC50 of 27 nM, 28 nM and 6.14 μM for IDH1 R132H , IDH1 R132C and IDH1 WT , respectively.TargetsIDH1R132H (Cell-free assay); IDH1R132C (Cell-free assay); IDH1WT (Cell-free assay) 27 nM; 28 nM; 6.14 μM

Dehydrogenase Inhibitors

Specifications & Purity: IDH-305 IDH-305 (Compound 13) is an orally available, mutant-selective and brain-penetrant inhibitor of isocitrate dehydrogenase 1 (IDH1) that targets IDH1(R132) mutation with IC50 of 27 nM, 28 nM and 6.14 μM for IDH1 R132H , IDH1 R132C and IDH1 WT , respectively.TargetsIDH1R132H (Cell-free assay); IDH1R132C (Cell-free assay); IDH1WT (Cell-free assay) 27 nM; 28 nM; 6.14 μM

Molecular Formula: C23H22F4N6O2

Molecular Weight: 490.45

PubChem CID: 90415637

Isomeric SMILES: CC1=CC(=NC=C1C2=CC(=NC=C2)C(F)(F)F)[C@H](C)NC3=NC=CC(=N3)N4[C@H](COC4=O)[C@H](C)F

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

42144301

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

I413032-1mg

Country of Origin:

China

CAS:

1628805-46-8

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90