IL-12 p40 Rat mAb (C007B-546407)

Rat anti Mouse IL-12 p40 Antibody, Monoclonal (C17.8), could be used for in vivo IL-12p40 neutralization, p40 affinity chromatography, IP, ELISA, Flow, WB and so on.Application:in vivo IL-12p40 neutralization: Use at an assay dependent concentration. p40 affinity chromatography: Use at an assay dependent concentration.IP: Use at an assay dependent concentration. ELISA: Use at an assay dependent concentration. Flow: Use at an assay dependent concentration. WB: Use at an assay dependent concentration.Protein FunctionCytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Specification: Carrier Free, Azide Free, Validated, ≥95%(SDS-PAGE), Lot by Lot

Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/AB109858-SCI_5ba9d45d3ca2ddb66e8f872621e609e0.pdf

UPC:

41116127

Condition:

New

Weight:

0.07 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

Ab109858-10μg

Product Size:

10μg