Sigma-Aldrich
INDY (C005B-312663)
Biochem/physiol Actions INDY is a potent inhibitor of Dyrk1A and Dyrk1B (dual-specificity tyrosine-phosphorylation-regulated kinase 1). The IC 50 values for inhibition of Dyrk1A and 1B are 240 and 230 nM, respectively.
Description
Biochem/physiol Actions
INDY is a potent inhibitor of Dyrk1A and Dyrk1B (dual-specificity tyrosine-phosphorylation-regulated kinase 1). The IC50 values for inhibition of Dyrk1A and 1B are 240 and 230 nM, respectively. INDY impairs the self-renewal capacity of neural stem cells and glioblastoma tumor-initiating cells.
Specifications
- UPC:
- 51112000
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 5
- Unit of Measurement:
- MG
- MPN:
- SML1011-5MG
- CAS:
- 1169755-45-6
Catalog No.
C005B-312663
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