General description
A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
caspase-8
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Warning
Toxicity: Irritant (B)
Sequence
Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*
Physical form
A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Analysis Note
≥98% (HPLC)
Other Notes
Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett.425, 61.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 51173008
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 218840-250UG
- Temperature Control Device:
- Yes
