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Sigma-Aldrich

ITX3 (C005B-034407)

Biochem/physiol Actions ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. The compound is active in whole cell assay where it inhibits the formation

Description

Biochem/physiol Actions

ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. The compound is active in whole cell assay where it inhibits the formation of TrioN-dependent cell structures. ITX3 appears to be specific for TrioN inhibition rather than other RhoGEFs.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GTP Binding Proteins (Low Molecular Weight) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Specifications
UPC:
51241904
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
25
Unit of Measurement:
MG
MPN:
I1411-25MG
CAS:
347323-96-0
Controlled Substances and Cyanide:
Yes
Catalog No. C005B-034407
Price: $538.89
List Price: $598.76
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