JHDM-IN-1

JHDM-IN-1 (Compound 1) is a Jumonji C domain-containing HDMs ( JHDM ) inhibitor with IC 50 s of 3.4, 4.3, 5.9, 10 and 43 μM against JMJD2C, JMJD2A, JMJD2E, PHF8 and JMJD3, respectivelyIn VitroJHDM-IN-1 (Compound 1) also inhibits FIH, PHD3, PHD1, PHD2 and LSD1 with IC 50 s of 22, 31, 54, 83 and 620 μM, respectively. JHDM-IN-1 (0-100 μM) does not inhibit KYSE150 cell growth after treatment for 48 h. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 3.4 μM (JMJD2C), 4.3 μM (JMJD2A), 5.9 μM (JMJD2E), 10 μM (PHF8), 22 μM (FIH), 31 μM (PHD3), 43 μM (JMJD3), 54 μM (PHD1), 83 μM (PHD2), 620 μM (LSD1). Molecular Formula: C27H29N3O6 Molecular Weight: 491.54

UPC:

51111746

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No;ManufacturerName=Aladdin Scientific"

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

J650309-1mg

CAS:

1310809-17-6

Product Size:

1mg

Controlled Substances and Cyanide:

Yes