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JNJ-61432059 (C007B-363129)

Catalog No.
C007B-363129
Mfr. No.
J656339-1ml
Mfr. Name
Aladdin Scientific
Qty/UOM
1
UOM
EA
Price: $513.01
List Price: $570.01

JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC 50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse

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JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC 50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse hippocampus, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant modelsIC50& Target:pIC50: 9.7 (AMPAR). Specification: 10mM in DMSO Molecular Formula: C25H22FN5O2 Molecular Weight: 443.5
UPC:
51332873
Condition:
New
Availability:
8-12 weeks
Weight:
1.06 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
J656339-1ml
CAS:
2035814-50-5
Product Size:
1ml

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