Aladdin Scientific
JNJ-61432059 (C007B-363129)
JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC 50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse
Description
JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC 50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse hippocampus, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant modelsIC50& Target:pIC50: 9.7 (AMPAR). Specification: 10mM in DMSO Molecular Formula: C25H22FN5O2 Molecular Weight: 443.5
Specifications
- UPC:
- 51332873
- Condition:
- New
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- J656339-1ml
- CAS:
- 2035814-50-5
- Product Size:
- 1ml
Catalog No.
C007B-363129
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