Kallikrein (C008B-265599)

Activation of Prekallikrein with Factor α-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.Extinction Coefficient (1%) = 11.7The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Specifications & Purity: Activation of Prekallikrein with Factor α-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.Extinction Coefficient (1%) = 11.7The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Grade: Bioactive;ActiBioPure™;Native;High Performance;EnzymoPure™

Storage Temperature: Store at 2-8°C

Shipped in: Wet ice

UPC:

51172472

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

H1443249-50μg

Country of Origin:

China

CAS:

410538-33-9

Product Size:

50μg

Harmonized Tariff Code:

2931.90.90