KI-67 (SP6) 7ML PREDILUTE (C15-1302-263)

General description

Ki-67 (MRQ-64) is an antibody designed to target Ki-67 antigen-a nuclear protein encoded by the MKI67 gene whose presence correlates with G1, S, G2, and the mitotic phases of the cell cycle.¹ Though its specific role is largely postulated and still yet to be determined, Ki-67′s presence during cellular division makes it an excellent target for labeling rapidly growing malignancies.² Given that its presence correlates with cell proliferation, the immunohistochemical labeling of Ki-67 antigen may be useful in characterizing a lesion′s growth fraction. It has been demonstrated that identifying this antigen by IHC is useful in characterizing lesions of the breast, lymphoid cells, astrocytes, and uterus.^3-9

Quality

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Linkage

Ki-67 Positive Control Slides, Product No. 275S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

biological source: rabbit. Quality Level: 100, 500. conjugate: unconjugated. antibody form: culture supernatant. antibody product type: primary antibodies. clone: MRQ-64, monoclonal. description: For In Vitro Diagnostic Use in Select Regions. form: buffered aqueous solution. species reactivity: human. packaging: vial of 0.1 . mL concentrate (275R-34), vial of 0.1 . mL concentrate Research Use Only (275R-34-RUO), vial of 0.5 . mL concentrate (275R-35), vial of 1.0 . mL concentrate (275R-36), vial of 1.0 . mL concentrate Research Use Only (275R-36-RUO), vial of 1.0 . mL pre-dilute Research Use Only (275R-37-RUO), vial of 1.0 . mL pre-dilute ready-to-use (275R-37), vial of 25.0 . mL pre-dilute ready-to-use (275R-30), vial of 25.0 . mL pre-dilute ready-to-use Research Use Only (275R-30-RUO), vial of 7.0 . mL pre-dilute ready-to-use (275R-38), vial of 7.0 . mL pre-dilute ready-to-use Research Use Only (275R-38-RUO). manufacturer/tradename: Cell Marque^™. . technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated). isotype: IgG. control: Burkitt lymphoma, breast (ductl carcinoma in situ), tonsil. shipped in: wet ice. storage temp.: 2-8°C. visualization: nuclear. Gene Information: human ... MKI67(4288). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.