KMUH(N-κ-maleimidoundecanoic acid hydrazide)

Product introduction:KMUH is a long, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).Features of KMUH:• :Reactive groups:maleimide andhydrazide:• :Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups:• Long (19.0A), sulfhydryl-to-aldehyde crosslinker with simple aliphatic spacer arm (noncleavable):• Maleimide group reacts with sulfhydryl groups to form stable thioether linkages:• Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates:• Usesodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups:• Use withEDC to conjugate primary amine of hydrazide group to carboxyl groups:Product References:Crosslinker Application Guide -- search for recent literature references for this product:• :Reactive Moiety:Amine,Hydrazide,Maleimide :• :Crosslinker Type:Heterobifunctional :• :Form:Solid :• :Spacer:Medium(10 to 30 Å) :• :Labeling Method:Chemical Labeling :• :Spacer Arm Length:19.0 Å. Molecular Weight: 409.4

UPC:

51241869

Condition:

New

Weight:

1.09 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

K638935-50mg

Product Size:

50mg