Kobusin

Kobusin is a bisepoxylignan isolated from the Pnonobio biondii Pamp. Kobusin is an activator of CFTR and CaCCgie chloride channels and a inhibitor of ANO1/CaCC (calcium-activated chloride channel) channel.In VitroKobusin could activate the function of CFTR and CaCCgie (CaCC expressed in gastrointestinal epithelial cells) chloride channels. Notably, Kobusin could inhibit the activities ANO1/CaCC chloride channel in ANO1/CaCC-expressing FRT cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoIn charcoal transit study, Kobusin mildly reduced gastrointestinal motility in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications & Purity: Kobusin is a bisepoxylignan isolated from the Pnonobio biondii Pamp. Kobusin is an activator of CFTR and CaCCgie chloride channels and a inhibitor of ANO1/CaCC (calcium-activated chloride channel) channel.In VitroKobusin could activate the function of CFTR and CaCCgie (CaCC expressed in gastrointestinal epithelial cells) chloride channels. Notably, Kobusin could inhibit the activities ANO1/CaCC chloride channel in ANO1/CaCC-expressing FRT cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoIn charcoal transit study, Kobusin mildly reduced gastrointestinal motility in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Grade: Moligand™

Molecular Formula: C21H22O6

Molecular Weight: 370.40

PubChem CID: 182278

Isomeric SMILES: COC1=C(C=C(C=C1)[C@@H]2[C@H]3CO[C@@H]([C@H]3CO2)C4=CC5=C(C=C4)OCO5)OC

Storage Temperature: Protected from light;Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51461525

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

K646346-25mg

Country of Origin:

China

CAS:

36150-23-9

Product Size:

25mg

Harmonized Tariff Code:

2931.90.90