L-372662 (C008B-271569)

L-372662 is a potent and orally active non-peptide oxytocin antagonist with a K i value of 4.8. The K d value of L-372662 for wild-type hOTR and [A318G]OTR is 5.8 nM and 73 nM. L-372662 shows selectivity to OTR:V 1a RIn VivoL-372662 is an antagonist of oxytocin-induced uterine contractions in late gestation pregnant rhesus monkeys (AD50 = 36 micrograms/kg), oral bioavailability (F = 90% in dogs), and aqueous solubility (10 mg/mL). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Ki: 4.8 (oxytocin)

Specifications & Purity: L-372662 is a potent and orally active non-peptide oxytocin antagonist with a K i value of 4.8. The K d value of L-372662 for wild-type hOTR and [A318G]OTR is 5.8 nM and 73 nM. L-372662 shows selectivity to OTR:V 1a RIn VivoL-372662 is an antagonist of oxytocin-induced uterine contractions in late gestation pregnant rhesus monkeys (AD50 = 36 micrograms/kg), oral bioavailability (F = 90% in dogs), and aqueous solubility (10 mg/mL). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Ki: 4.8 (oxytocin)

Grade: Moligand™

Molecular Formula: C33H38N4O6

Molecular Weight: 586.68

PubChem CID: 5311202

Isomeric SMILES: CC1=C(C=CC=[N+]1[O-])CN2CCC(CC2)OC3=CC(=C(C=C3)C(=O)N4CCC(CC4)N5C6=CC=CC=C6COC5=O)OC

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51373422

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

L646313-100mg

Country of Origin:

China

CAS:

162045-26-3

Product Size:

100mg

Harmonized Tariff Code:

2931.90.90