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13297-1A tyrphostin that is a poor inhibitor of EGFRK (IC<sub>50</sub> = 450 &muM) and PDGFRK (IC<sub>50</sub> > 100 &muM) which has been found to inhibit the phosphorylation of ERK1 and ERK2 at 25-50 &muM blocks the production of TNF-&alpha,
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13297-10A tyrphostin that is a poor inhibitor of EGFRK (IC<sub>50</sub> = 450 &muM) and PDGFRK (IC<sub>50</sub> > 100 &muM) which has been found to inhibit the phosphorylation of ERK1 and ERK2 at 25-50 &muM blocks the production of TNF-&alpha,
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13297-25A tyrphostin that is a poor inhibitor of EGFRK (IC<sub>50</sub> = 450 &muM) and PDGFRK (IC<sub>50</sub> > 100 &muM) which has been found to inhibit the phosphorylation of ERK1 and ERK2 at 25-50 &muM blocks the production of TNF-&alpha,
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13297-5A tyrphostin that is a poor inhibitor of EGFRK (IC<sub>50</sub> = 450 &muM) and PDGFRK (IC<sub>50</sub> > 100 &muM) which has been found to inhibit the phosphorylation of ERK1 and ERK2 at 25-50 &muM blocks the production of TNF-&alpha,
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14529-1A quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC<sub>50</sub>s range from 0.3-1 µM) inhibits PDGF-stimulated DNA synthesis (IC<sub>50</sub> = 2.
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14529-10A quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC<sub>50</sub>s range from 0.3-1 µM) inhibits PDGF-stimulated DNA synthesis (IC<sub>50</sub> = 2.
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14529-25A quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC<sub>50</sub>s range from 0.3-1 µM) inhibits PDGF-stimulated DNA synthesis (IC<sub>50</sub> = 2.
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14529-5A quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC<sub>50</sub>s range from 0.3-1 µM) inhibits PDGF-stimulated DNA synthesis (IC<sub>50</sub> = 2.
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10010592-1A potent and selective inhibitor of PDGF receptor kinase with an IC50 value of about 0.4 µM both in vitro and in cells (Swiss 3T3 cells).
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10010592-10A potent and selective inhibitor of PDGF receptor kinase with an IC50 value of about 0.4 µM both in vitro and in cells (Swiss 3T3 cells).