Biologically Active Small Molecules

Commonly used as a pH indicator, a color marker in agarose or polyacrylamide gel electrophoresis, and a dye to detect proteins and nucleic acids (absorbance at 610 nm), particularly when staining living tissues.

Commonly used as a pH indicator, a color marker in agarose or polyacrylamide gel electrophoresis, and a dye to detect proteins and nucleic acids (absorbance at 610 nm), particularly when staining living tissues.

A non-selective bromodomain inhibitor that at 1 &microM has been shown to accelerate FRAP recovery of BRD4 and CREBBP bromodomains in HeLa cells.

A non-selective bromodomain inhibitor that at 1 &microM has been shown to accelerate FRAP recovery of BRD4 and CREBBP bromodomains in HeLa cells.

A non-selective bromodomain inhibitor that at 1 &microM has been shown to accelerate FRAP recovery of BRD4 and CREBBP bromodomains in HeLa cells.

A non-selective bromodomain inhibitor that at 1 &microM has been shown to accelerate FRAP recovery of BRD4 and CREBBP bromodomains in HeLa cells.

BS-181 is a Cdk7 inhibitor that blocks the activity of Cdk-activating kinase with an IC₅₀ value of 21 nM.1 It inhibits Cdk2 at a concentration 35-fold higher than that of Cdk7.

BS-181 is a Cdk7 inhibitor that blocks the activity of Cdk-activating kinase with an IC₅₀ value of 21 nM.1 It inhibits Cdk2 at a concentration 35-fold higher than that of Cdk7.

BS-181 is a Cdk7 inhibitor that blocks the activity of Cdk-activating kinase with an IC₅₀ value of 21 nM.1 It inhibits Cdk2 at a concentration 35-fold higher than that of Cdk7.

BS-181 is a Cdk7 inhibitor that blocks the activity of Cdk-activating kinase with an IC₅₀ value of 21 nM.1 It inhibits Cdk2 at a concentration 35-fold higher than that of Cdk7.

An irreversible, noncompetitive inhibitor of PARP1 that disrupts binding between PARP1 and DNA by interacting with the DNA binding domain produces rapid apoptosis in the various cancer cell (IC50s = 40-128 &muM).

An irreversible, noncompetitive inhibitor of PARP1 that disrupts binding between PARP1 and DNA by interacting with the DNA binding domain produces rapid apoptosis in the various cancer cell (IC50s = 40-128 &muM).