CAYMAN CHEMICAL
-Lapachone-10 mg
A quinone which inhibits topoisomerase I at 25 &muM and transglutaminase (IC50 = 5 &muM) reduced to &beta-lapachone hydroquinone by NQO1, generating ROS during its reversion to &beta-lapachone sensitizes cancer cells to radiation,
Description
A quinone which inhibits topoisomerase I at 25 μM and transglutaminase (IC50 = 5 μM); reduced to β-lapachone hydroquinone by NQO1, generating ROS during its reversion to β-lapachone; sensitizes cancer cells to radiation, suppresses NF-κB activation, and drives apoptosis.
Specifications
- UPC:
- 51111619
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- 15021-10
- CAS:
- 4707-32-8
Catalog No.
C003B-520728
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