LDN-27219 (C15-1724-846)

Catalog No.: C15-1724-846
Mfr. No.: SML0744-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $295.70

List Price: $328.55

Biochem/physiol Actions LDN-27219 is a revesible inhibitor of transglutaminase 2 (TG2) that binds to the GTP binidng site of the enzyme and inhbits activity with and IC 50 of 600 nM. LDN-27219 is a thieno[2,3-d]pyrimidine-4-one-acylhydrazide

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Description
Specifications

Biochem/physiol Actions

LDN-27219 is a revesible inhibitor of transglutaminase 2 (TG2) that binds to the GTP binidng site of the enzyme and inhbits activity with and IC₅₀ of 600 nM.

LDN-27219 is a thieno[2,3-d]pyrimidine-4-one-acylhydrazide derivative. Closed conformation of TG2 induced by LDN-27219 can be a potential therapeutic strategy for age-related vascular dysfunction and lowering blood pressure.

UPC:: 51432807
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0744-5MG
CAS:: 312946-37-5

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