Sigma-Aldrich
LDN-27219 (C005B-313014)
Biochem/physiol Actions LDN-27219 is a revesible inhibitor of transglutaminase 2 (TG2) that binds to the GTP binidng site of the enzyme and inhbits activity with and IC 50 of 600 nM. LDN-27219 is a thieno[2,3-d]pyrimidine-4-one-acylhydrazide
Description
Biochem/physiol Actions
LDN-27219 is a revesible inhibitor of transglutaminase 2 (TG2) that binds to the GTP binidng site of the enzyme and inhbits activity with and IC50 of 600 nM.
LDN-27219 is a thieno[2,3-d]pyrimidine-4-one-acylhydrazide derivative. Closed conformation of TG2 induced by LDN-27219 can be a potential therapeutic strategy for age-related vascular dysfunction and lowering blood pressure.
Specifications
- UPC:
- 51432807
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 25
- Unit of Measurement:
- MG
- MPN:
- SML0744-25MG
- CAS:
- 312946-37-5
Catalog No.
C005B-313014
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