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CAYMAN CHEMICAL

Lenvatinib-25 mg

Lenvatinib is a potent inhibitor of VEGF-R2 and VEGF-R3 kinase activities with IC50 values of 4.0 and 5.

Description

Lenvatinib is a potent inhibitor of VEGF-R2 and VEGF-R3 kinase activities with IC50 values of 4.0 and 5.2 nM, respectively.. It is slightly less potent against the related receptor kinases VEGF-R1, FGF-R1, PGDFR3β and Kit (IC50 values of 22, 46, 39, and 100 nM, respectively). It is orally active, inhibiting H136 cell tumor growth in mice at 30 mg/kg.


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Specifications
UPC:
51112000
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No"
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
19375-25
Model Number:
C814C18
Temperature Control Device:
Yes
Catalog No. C003B-120985
Price: $826.86
List Price: $918.73
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