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Sigma-Aldrich

LEUCINOSTATIN A+B MIXTURE

Biochem/physiol Actions Leucinostatins A and B are the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus . Leucinostatins display broad bio-activity against gram-positive bacteria, fungi, plants and tumor

Description

Biochem/physiol Actions

Leucinostatins A and B are the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus. Leucinostatins display broad bio-activity against gram-positive bacteria, fungi, plants and tumor cell lines. They play a role as uncouplers in the inner mitochondria membrane and inhibit mitochondrial ATP synthesis. Recently, interest in Leucinostatins has focused on other aspects such as understanding their activity: insulin-like growth factor I regulators, ionophore, inhibitors of cell surface expression of viral glycoproteins and their potent in vitro and in vivo anti-trypanosomal activity.

Components

Mixture of Leucinostatin A (Cas# 76600-38-9 / MF: C62H111N11O13) and Leucinostatin B (Cas# 76663-52-0 / MF: C61H109N11O13).

Other Notes

Stable at −20 °C for at least 2 years.

Specifications
UPC:
51282328
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
1
Unit of Measurement:
MG
MPN:
SML1566-1MG
Catalog No. C005B-311920
Price: $565.07
List Price: $627.86
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