Activin and Inhibin

CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC 50 s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA , respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD)IC50&amp:

CDK7-IN-2 is a potent inhibitor of CDK7. CDK7 is implicated in both temporal control of the cell cycle and transcriptional activity. CDK7 is implicated in the transcriptional initiation process by phosphorylation of Rbpl subunit of RNA Polymerase II

CDK7-IN-2 is a potent inhibitor of CDK7. CDK7 is implicated in both temporal control of the cell cycle and transcriptional activity. CDK7 is implicated in the transcriptional initiation process by phosphorylation of Rbpl subunit of RNA Polymerase II

CDK7-IN-2 is a potent inhibitor of CDK7. CDK7 is implicated in both temporal control of the cell cycle and transcriptional activity. CDK7 is implicated in the transcriptional initiation process by phosphorylation of Rbpl subunit of RNA Polymerase II

CDK7-IN-2 is a potent inhibitor of CDK7. CDK7 is implicated in both temporal control of the cell cycle and transcriptional activity. CDK7 is implicated in the transcriptional initiation process by phosphorylation of Rbpl subunit of RNA Polymerase II

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC 50 of 3 nM.In VivoCDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The t max is 0.25 h by PO. The mean values of C max are 9940 μg/L, 12740 μg/L by

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC 50 of 3 nM.In VivoCDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The t max is 0.25 h by PO. The mean values of C max are 9940 μg/L, 12740 μg/L by

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC 50 of 3 nM.In VivoCDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The t max is 0.25 h by PO. The mean values of C max are 9940 μg/L, 12740 μg/L by

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC 50 of 3 nM.In VivoCDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The t max is 0.25 h by PO. The mean values of C max are 9940 μg/L, 12740 μg/L by

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC 50 of 3 nM.In VivoCDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The t max is 0.25 h by PO. The mean values of C max are 9940 μg/L, 12740 μg/L by

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC 50 of 3 nM.In VivoCDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The t max is 0.25 h by PO. The mean values of C max are 9940 μg/L, 12740 μg/L by

CDK8-IN-3 is an inhibitor of CDK8 extracted from patent WO2016041618A1, compound example 1.7.Form:Solid.