LONGDAYSIN (C15-1725-599)

Catalog No.: C15-1725-599
Mfr. No.: SML0127-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $312.20

List Price: $346.88

Application Longdaysin may be used to study cell signaling that regulate the circadian clock and behavior. Biochem/physiol Actions Longdaysin inhibits CK1, ERK2, and CDK7 kinases in low mM concentrations.

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Description
Specifications

Application

Longdaysin may be used to study cell signaling that regulate the circadian clock and behavior.

Biochem/physiol Actions

Longdaysin inhibits CK1, ERK2, and CDK7 kinases in low mM concentrations. The activity of longdaysin results in a lengthening of circadian periods in cell based and in vivo systems. Transgenic zebrafish harboring a per3-luc reporter gene displayed a 10 hour lengthening of circadian period when treated with longdaysin. Longdaysin reduces the phosphorylation of PER1 the regulator of molecular clock function and manipulates the circadian clock.

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Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.

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UPC:: 51281666
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: Yes
MPN:: SML0127-5MG

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