LONGDAYSIN (C005B-313759)

Application

Longdaysin may be used to study cell signaling that regulate the circadian clock and behavior.

Biochem/physiol Actions

Longdaysin inhibits CK1, ERK2, and CDK7 kinases in low mM concentrations. The activity of longdaysin results in a lengthening of circadian periods in cell based and in vivo systems. Transgenic zebrafish harboring a per3-luc reporter gene displayed a 10 hour lengthening of circadian period when treated with longdaysin. Longdaysin reduces the phosphorylation of PER1 the regulator of molecular clock function and manipulates the circadian clock.

Shipping Information:

Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.

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UPC:

51281612

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

Yes

Quantity:

25

Unit of Measurement:

MG

MPN:

SML0127-25MG