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Sigma-Aldrich

LOSARTAN POTASSIUM (C005B-012825)

Losartan potassium has long lasting effects, and its efficacy is generally increased, when combined with the diuretic co-active hydrochlorothiazide. Losartan potassium is an antihypertensive drug that is found to be an angiotensin II receptor type

Description

General description

Losartan potassium has long lasting effects, and its efficacy is generally increased, when combined with the diuretic co-active hydrochlorothiazide.

Losartan potassium is an antihypertensive drug that is found to be an angiotensin II receptor type 1 blocker. It finds applications in reducing mechanical stress thereby having a control over the condition of cardiac hypertrophy.

Application

Losartan potassium may be used as an analytical reference standard for the quantification of the analyte in the following:

  • Pharmaceutical formulations using reversed-phase high-performance liquid chromatography and UV-spectrophotometric techniques.
  • Rat plasma using liquid chromatography€“tandem mass spectrometry (LC€“MS/MS) technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension.

Specifications
UPC:
51432313
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
100
Unit of Measurement:
MG
MPN:
61188-100MG-9
CAS:
124750-99-8
Catalog No. C005B-012825
Price: $425.04
List Price: $472.27
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