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CAYMAN CHEMICAL

LY255283-1 mg

An alkaloid that inhibits the growth of mouse leukemia P388 cells (IC50 = 1.8 &mug/ml) binds to and stabilizes the topoisomerase I-DNA binary complex, leading to DNA breakage and cell death (IC50 = 5.

Description
An alkaloid that inhibits the growth of mouse leukemia P388 cells (IC50 = 1.8 μg/ml); binds to and stabilizes the topoisomerase I-DNA binary complex, leading to DNA breakage and cell death (IC50 = 5.07-12.6 μM); selectively inhibits CYP1A1 and CYP1A2 (IC50 = ~6 μM for each) in human liver microsomes.
Specifications
UPC:
51112005
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
70715-1
Catalog No. C003B-360386
Price: $142.25
List Price: $158.06
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