LY900009 (C008B-268028)

LY900009 is a potent and orally active, First-in-class inhibitor of Notch signaling via selective inhibition of the γ-secretase protein (GSI). LY900009 inhibited Notch signalling in tumor cell lines and endothelial cells (IC 50 range: 0.005-20 nM). LY900009 can be used for advanced cancer research.In VivoLY900009 (oral gavage; 3 mg/kg; single dosage) revealed inhibition of angiogenesis through formation of leaky vasculature and produced tumour regression in Notch-dependent tumour models in a rat model . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid

Specifications & Purity: LY900009 is a potent and orally active, First-in-class inhibitor of Notch signaling via selective inhibition of the γ-secretase protein (GSI). LY900009 inhibited Notch signalling in tumor cell lines and endothelial cells (IC 50 range: 0.005-20 nM). LY900009 can be used for advanced cancer research.In VivoLY900009 (oral gavage; 3 mg/kg; single dosage) revealed inhibition of angiogenesis through formation of leaky vasculature and produced tumour regression in Notch-dependent tumour models in a rat model . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid

Grade: Moligand™

Molecular Formula: C23H27N3O4

Molecular Weight: 409.48

PubChem CID: 57327010

Isomeric SMILES: C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)[C@H](C(C)C)O

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51292804

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

L649118-100mg

Country of Origin:

China

CAS:

209984-68-9

Product Size:

100mg

Harmonized Tariff Code:

2931.90.90