Lys-CoA TFA (C007B-365114)

Lys-CoA TFA is a selective p300 histone acetyltransferase (HAT) inhibitor ( IC 50 =50-500 nM). Lys-CoA TFA displays >100-fold selectivity for p300 over PCAF (IC 50 =200 μM). Lys-CoA TFA inhibits p300 HAT activity-dependent transcriptional activation.Appearance:SolidIC50& Target:p300 50-500 nM (IC 50 )In Vitro:Lys-CoA TFA (0.1 and 1 mM; 60 hours) induces a senescent phenotype in human normal melanocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: Normal human melanBiological Activity:Lys-CoA TFA is a selective p300 histone acetyltransferase (HAT) inhibitor ( IC 50 =50-500 nM). Lys-CoA TFA displays >100-fold selectivity for p300 over PCAF (IC 50 =200 μM). Lys-CoA TFA inhibits p300 HAT activity-dependent transcriptional activation. Specification: 0.99 Molecular Formula: C33H54F3N10O21P3S Molecular Weight: 1108.82

UPC:

51202421

Condition:

New

Weight:

1.09 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

L658820-5mg

Product Size:

5mg