Carazolol

A high-affinity, lipophilic, non-selective ligand of the &beta-adrenergic receptors (Kis = 0.114 and 0.

A high-affinity, lipophilic, non-selective ligand of the &beta-adrenergic receptors (Kis = 0.114 and 0.

A high-affinity, lipophilic, non-selective ligand of the &beta-adrenergic receptors (Kis = 0.114 and 0.

A high-affinity, lipophilic, non-selective ligand of the &beta-adrenergic receptors (Kis = 0.114 and 0.

A cell permeable pyrazol derivative that acts as a specific CRAC (Ca 2+ release-activated Ca 2+ entry) channel blocker (IC 50 = 800 nM in RBL cells) possibly downstream of STIM1 oligomerization and STIM1/Orail interaction. Shown to fully block

Biochem/physiol Actions &#945:-adrenoceptor agonist: imidazoline binding site ligand. Features and Benefits This compound was developed by Novartis .