Piritrexim

Anti-PIDD1 p53-induced death domain protein 1, 25ul UN 1687

Biochem/physiol Actions BG-3 is a cell penetrant, potent and selective inhibitor of Pax2 (paired-box 2) that inhibits Pax2 transactivation ability. BG-3 inhibit the ability of Pax proteins to recruit PTIP and promote H3K4 methylation at Pax

Biochem/physiol Actions BG-3 is a cell penetrant, potent and selective inhibitor of Pax2 (paired-box 2) that inhibits Pax2 transactivation ability. BG-3 inhibit the ability of Pax proteins to recruit PTIP and promote H3K4 methylation at Pax

Biochem/physiol Actions Brassinin is a phytoalexin isolated from cruciferous vegetables that exhibits anticancer, chemopreventive, antiproliferative and antifungal activities. In lung cancer cells, brassinin inhibits constitutive and

A potent, reversible, orally bioavailable inhibitor of Pim-1, -2, and -3 (IC₅₀s = 5, 25, and 16 nM, respectively) dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1 acts synergistically with

A potent, reversible, orally bioavailable inhibitor of Pim-1, -2, and -3 (IC₅₀s = 5, 25, and 16 nM, respectively) dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1 acts synergistically with

A potent, reversible, orally bioavailable inhibitor of Pim-1, -2, and -3 (IC₅₀s = 5, 25, and 16 nM, respectively) dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1 acts synergistically with

A potent, reversible, orally bioavailable inhibitor of Pim-1, -2, and -3 (IC₅₀s = 5, 25, and 16 nM, respectively) dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1 acts synergistically with

A cell-permeable benzimidazole compound that inhibits Akt phosphorylation/activation presumably by targeting the ATP binding site of a kinase upstream of Akt, but downstream of PI3K. Shown to block Akt-mediated FOXO1a nuclear export (IC 50 = 625

General description The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer (Dhanasekaran et al., 2001 [PubMed 11518967]).

General description The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer (Dhanasekaran et al., 2001 [PubMed 11518967]).

General description The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer (Dhanasekaran et al., 2001 [PubMed 11518967]).