Methyl chloroformate

Application

Methyl chloroformate (MCF) is generally used for the derivatization of functional groups such as carboxylic acids, amines, and phenols.
MCF can also be used:

• To activate 3-acylpyridines for nucleophilic addition with alkynyltin reagents to form 2,3-disubstituted 1,2-dihydropyridines.
• Chloroesterification of terminal alkynes to form β-chloro-α,β-unsaturated esters.
• As an electrophilic reagent to mediate the reaction of pyridine with lithium dialkyl- or diarylcuprates to form 4-substituted 1,4-dihydropyridine derivatives.
• To convert nitronates into methoxycarbonyl nitronates.

UPC:

51412502

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

5

Unit of Measurement:

G

WeightUOM:

LB

MPN:

M35304

CAS Number:

79-22-1