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Sigma-Aldrich

METHYL ISONIPECOTATE TECHNICAL GRADE

Methyl isonipecotate can be obtained by the reduction of methyl isonicotinate in methanol with ruthenium at 100-150°C. Application Methyl isonipecotate may be used for the synthesis of a series of potent non-urea soluble epoxide hydrolase (sE

Description

General description

Methyl isonipecotate can be obtained by the reduction of methyl isonicotinate in methanol with ruthenium at 100-150°C.

Application

Methyl isonipecotate may be used for the synthesis of a series of potent non-urea soluble epoxide hydrolase (sEH) inhibitors via high throughput screens.

Precipitate may form upon standing which should not affect application.

Reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation

Reactant for synthesis of:
Antitubercular agents
Anti-HIV-1 agents
Aminopyrazine inhibitors
Orally available naphthyridine protein kinase D inhibitors
A Scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide

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Specifications
UPC:
51372300
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
Yes
Quantity:
25
Unit of Measurement:
ML
MPN:
463485-25ML
CAS:
2971-79-1
Controlled Substances and Cyanide:
Yes
Catalog No. C005B-030045
Price: $163.92
List Price: $182.13
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