General description
Glycophorin A, CD235a, is a single-pass membrane sialoglycoprotein and carrier of the blood group specificities M and N. The gene is located on chromosome 4q28-q31 and share sequence homology with genes encoding glycophorin B and glycophorin E (van der Schoot, 2002). Glycophorin A is expressed by erythroid cells beginning on morphologically recognizable erythroid precursors, just after the CFU-E stage, to the mature erythrocyte. Once glycophorin A is maximally expressed, the amount in each erythroid cell remains constant and does not appear to change during further maturation (Loken, 1987).
Specificity
Antibody recognizes Human CD235a antigen.
Immunogen
Membrane extracts of hairy cell leukemia prepared from human spleen
Application
Detect CD235a using this Milli-Mark Anti-CD235a-FITC Antibody, clone JC159 validated for use in FC.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Quality
Evaluated by flow cytometry using human lymphocytes
Target description
16 kDa (calculated)
Physical form
Protein A purified
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Storage and Stability
Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Analysis Note
Control
Human Lymphocytes
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- UPC:
- 41116126
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- FCMAB217F
